All authors confirmed the final manuscript. In the immunofluorescence staining experiment, a-SMA was mainly in myofibroblasts, and the fluorescence was red. Rather, Ge Xia Zhu Yu Tang is used to treat patterns that are sometimes the root cause behind scanty menstruation. Citation: Cao X, Liang Y, Liu R, Zao X, Zhang J, Chen G, Liu R, Chen H, He Y, Zhang J and Ye Y (2022) Uncovering the Pharmacological Mechanisms of Gexia-Zhuyu Formula (GXZY) in Treating Liver Cirrhosis by an Integrative Pharmacology Strategy. Consultation Support. Data were expressed as the mean ± SD, 2 groups using student's t-test and more than 2 groups using one-way ANOVA. T000800773, Zhejiang, China; 6g), Corydalis Rhizome (Yanhusuo in Chinese, No. Ge xia zhu yu tang for dogs. This pattern leads to symptoms such as dark face, purple lips, boring fixed stabbing pain and abdominal masses. The GO-CC analysis showed the main targets to be mainly enriched in the cytosol, nucleus, and nucleoplasm (Figure 3C).
With Chi Shao, for gynecological disorders due to Blood Stasis. We slightly regretted that the changing trend of other key genes in rats and LX2 cells is not consistent in the intervention of GXZY. XC, HC, and RL conducted the cell experiments. DAVID: Database for Annotation, Visualization, and Integrated Discovery. Breast distention distention and pain. Jing Tang Ge Xia Zhu Yu Concentrated 90g Powder. Polycystic ovary system. Danggui Buxue Tang (Astragali Radix and Angelicae Sinensis Radix) for Menopausal Symptoms: A Review.
In order to further explore the mechanisms of GXZY in the treatment of LC, we observed the expression of inflammatory factors and key genes in each group of rats at the 12th week, and Actb (β-action) was an internal parameter. By clicking "Accept", you agree to our website's cookie use as described in our Cookie Policy. Ge xia zhu yu tang powder. HBV hepatitis B virus. In addition, AR was expressed at low levels in the liver and could be prone to measurement errors. Actions: Calms pain. Therefore, it is still necessary to explore the therapeutic effect and mechanisms of TCM compound prescription in anti-liver fibrosis and cirrhosis to find a novel and safe prevention strategy. FORMULAS THAT INVIGORATE THE BLOOD AND DISPEL BLOOD STASIS: ACTIONS: Invigorates the Blood; Dispels Blood stasis; Promotes the movement of Qi; Alleviates pain INDICATIONS: For Blood stasis in the area below the diaphragm with palpable abdominal masses accompanied by fixed pain, or abdominal masses that are visible when lying down; Also for chronic diarrhea and daybreak diarrhea; Also commonly used to treat amenorrhea and painful periods TONGUE: PULSE: Terms in this set (12).
01 versus the control group, and ## p < 0. A Systems Biology-Based Investigation into the Therapeutic Effects of Gansui Banxia Tang on Reversing the Imbalanced Network of Hepatocellular Carcinoma. Invigorate blood, alleviate pain - pain from blood stasis and trauma, dysmenorrhea. The scratch areas were quantified using Imagepro-plus 6. Zhang, W., Huai, Y., Miao, Z., Qian, A., and Wang, Y. Ge Xia Zhu Yu Tang › Veterinarian Recommended Holistic Pet Products. And the key targets were significantly related to multiple GO-BP, including response to drug, negative regulation of apoptotic process, and positive regulation of transcription, DNA-templated (Figure 3B). Collection of Chemical Compounds in GXZY. SwissTargetPrediction: Updated Data and New Features for Efficient Prediction of Protein Targets of Small Molecules. Truncated intro ".. with blood circulation may lead to generalized pain and fatigue to fixed masses.
For any other type of acute trauma to the body. About the item: Brand: Blue Poppy. Invigorates the Blood, dispels Blood Stasis and relieves pain. In Chinese Medicine health conditions are thought to arise due to "disharmonies" in the body as a system. Identification of LC Targets. Network Pharmacology-Based Analysis. Ge xia zhu yu tang bee. 0 () (Kohl et al., 2011). Romaji: Kakka Chikuo To. The studies have shown that inhibition of HBV and intrahepatic inflammation can delay or even reverse the progression of cirrhosis.
A range of pain related issues when they arise from qi and blood stagnation (both acute and chronic) - pain essentially anywhere in the body, bruises and swelling and other signs of stasis. After eliminating the redundancy, a total of 1440 putative targets were collected (Supplementary Table S4). Uncovering the Pharmacological Mechanisms of Gexia-Zhuyu Formula (GXZY) in Treating Liver Cirrhosis by an Integrative Pharmacology Strategy. Network Construction. With Chuan Xiong, harmonizes, nourishes and invigorates the Blood and disperses Blood Stasis for abdominal pain and irregular menstruation due to Blood Deficiency with Qi Stagnation.
Pain of all types from qi and blood stagnation - often combined with other more systemic formulas based on the individual. We acquired a dense region network of 7 key targets (Figure 2C), including AR, JUN, MYC, CASP3, MMP9, RELA, and GAPDH. Liver Qi Stagnation with Blood Blockage in the area below the diaphragm. With Tao Ren, for menstrual problems due to Blood Stagnation. Retail Price: Retails. Because of its reliable curative effect and few side effects, it is becoming more and more popular in western countries. 5 and limited to Homo sapiens species. Page: The following combinations are available for this ingredient. Please see Strategic Dosing Guidelines for details. LX-2 cells were treated dose-increased GXZY, and the cell viability was detected with CCK-8. Note that Natural Path and Kan Essentials products are currently undergoing registration with Health Canada as Natural Health Products. In LX2 cells experiment, GXZY could reduce expression of CASP3, which is consistent with previous studies, and salvianolic acid A could reduce the expressions of CASP3 and liver fibrosis (Wang et al., 2019). 0 statistical software package. However, its pharmacological mechanisms on LC remain elucidated.
Cornerstone Technology. Pulse type(s): Wiry (Xian). Register with to enjoy personalized service including: Online Order Status. GXZY Gexia-Zhuyu formula. Kornberg, M., Bhargava, P., Kim, P., Putluri, V., Snowman, A., and Putluri, N. (2018). Promotes circulation and dispels Bi Pain.
Liver tissue slices were cultured in primary antibody, a-SMA antibody (1:500), and anti-CD68 (1:100) at 4°C overnight and then cultured in secondary antibodies, goat anti-rabbit IgG antibody (1:100), and goat anti-mouse IgG (1:100) conjugated at room temperature for 2 h. And the sections of different groups were photographed by using a multifunctional confocal microscope (Olympus, Tokyo, Japan). With Xiang Fu, for flank pain, abdominal pain, and dysmenorrhea due to Qi and Blood Stagnation. Category: Herbs that regulate Qi. Blood stagnation particularly in the head - migraines and/or headaches with other sensory factors - auras, sound sensitivity, etc. Daina, A., Michielin, O., and Zoete, V. (2019). YY and JZ put forward an overall concept. TCM traditional Chinese medicine. Secretary of Commerce. As a global company based in the US with operations in other countries, Etsy must comply with economic sanctions and trade restrictions, including, but not limited to, those implemented by the Office of Foreign Assets Control ("OFAC") of the US Department of the Treasury. GXZY reduced the expression of inflammatory factors and Mmp9 in rat liver. P: Wiry, choppy and tight. Next, 12 h later, the cell monolayer was scratched with a sterile 10-μl pipette tip to generate a line-shaped wound.
Packaging: 100 g/bt. Liu, P., Shang, E. X., Zhu, Y., Yu, J. G., Qian, D. W., and Duan, J. According to qRT-PCR experiment, GXZY down-regulated MMP9, which was consistent in animal and cell experiments. We treated LX2 cells with GXZY and detected the cell proliferation viability and migration activity. Note: Nothing on this site should be construed as a claim of efficacy for any symptom or disease. Hemiplegia, slurred speech or involuntary muscle control due to blockage of the channels and collaterals. An aqueous extract of GXZY was used for blood stasis, and it was found that GXZY affects liver cirrhosis in animal experiments (Chen et al., 2012; Deng et al., 2019). In general Gan Cao's main actions are as follows: "Tonifies the Basal Qi and nourishes the Spleen Qi. Members are generally not permitted to list, buy, or sell items that originate from sanctioned areas. 2 Institute of Liver Diseases, Beijing University of Chinese Medicine, Beijing, China. Chapter: Regulate the Blood. Chinese Brand: 梅花牌®.
The 6-inch-scale Black Series figure is detailed to look like the Ben Kenobi (Tibidon Station) character from. Product Details Specification Reviews Delivery & Returns. Click here to Register. OBI-WAN KENOBI (TIBIDON STATION) Star Wars The Black Series. And I opt in to receive commercial and promotional emails. Former Jedi and General of the Grand Army of the Republic, he now lives a life of obscurity, hidden from the world at large. Our package will be courier-proof.
Browse Similar Items. Login to your account. Comics and cartoons. Series-based character-inspired accessories: this star wars the black series action figure comes with 3 entertainment-inspired accessories that make a great addition to any star wars collection. As seen in Star Wars: Obi-Wan Kenobi, get yourself a Star Wars Black Series Ben Kenobi (Tibidon Station) before an Inquisitor finds him first!
Il Pop è arrivato nei tempi previsti, in ottime condizioni e impacchettato con cura. Create an account and start saving immediately, for you 100 points for free when you create your account. Your account will remain active for 45 days. You can either agree or not to continue. General Terms and Conditions of Use and Sale. Le nostre spedizioni garantiscono l'arrivo del prodotto nelle migliori condizioni possibili. UEFA Champions League. Hasbro Star Wars The Black Series Obi-Wan Kenobi Ben Kenobi (Tibidon Station) Target Exclusive Action Figure. With her double lightsaber extended, the Third Sister Inquisitor is ready for action. Hasbro's Star Wars: The Black Series line unleashes new figures of the Jedi Master and former apprentice Darth Vader among new reveals this week. Limited 2 per customers.
Collector's Club Discount Program (5% Discount). Usiamo il corriere GLS Italy, che garantisce consegne in 24/48 ore a partire dalla presa in carico del prodotto da parte del corriere stesso. Star Wars The Black Series Obi-Wan Kenobi 06 Ben Kenobi Tibidon Station via * Feb, 10 8:19 PM EST $21. Model Number: - F5604. Sito consigliato con ottimi prezzo e molto disponibili, cordiali e veloci nelle risposte.
Reference: SS400369. Open / Damaged or Repacked box. STAR WARS OBI-WAN KENOBI BLACK SERIES BEN KENOBI TIBIDON STATION (ACTION FIGURE). Active auctions are not calculated into the price history graph. Payment using Cryptocurrency available! Alternative clothing. Marvel Legends Retro Spider-Man (7) Figures Complete Bundle. Availability: Join Waiting List. Classic comic strips.
The backpack can be opened and you can place a few accessories inside. Boba Fett's Starfighter Premium 3D Metal Earth Model Kit. First Access To Back In Stock Items. Hasbro owns the trademarks and products of Kenner, Parker Brothers, and Milton Bradley, among others. The belt is sculpted onto the body and not removable.
Sw Retro Fifth Brother Af Action Figure. Product Contains: - Includes: Figure and 3 accessories. Approved Selection box. Obi-Wan came with a blaster, a soft-goods cape, a lightsaber with detachable blue blade and a backpack. Leicester City F. C. Paris Saint-Germain. 1/6 scale figure & speeder bike. Do you want your experience to be unique? Sw Bl Magistrate Greef Karga Af Action Figure. Factory remanufactured. 2 kilograms to 30kg for Speedpost to Australia, France and the United States. Reference: HASF5531. Il prodotto è perfettamente in linea con la descrizione. Early Access To New Drops.